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D’Souza, Sonal
- Antiepileptic Activity of Ethanolic and Aqeous Leaves Extract of Annona reticulata Linn
Abstract Views :163 |
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Authors
Sonal D’Souza
1,
Jennifer Fernandes
1,
M. Vijay Kumar
1,
Nishmitha Gretta D’Souza
1,
Ronald Fernandes
1
Affiliations
1 Department of Pharmaceutical Chemistry, N.G.S.M. Institute of Pharmaceutical Sciences, Nitte (Deemed to be University) Paneer, Deralakatte, Mangalore-575018, IN
1 Department of Pharmaceutical Chemistry, N.G.S.M. Institute of Pharmaceutical Sciences, Nitte (Deemed to be University) Paneer, Deralakatte, Mangalore-575018, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 1 (2019), Pagination: 241-244Abstract
The present study was evaluated for the Antiepileptic activity of methanolic and aqeous extracts of leaves Annona reticulata on the seizures induced by chemical and electroconvulsive method i.e PTZ and MES methods. In this study, the antiepileptic study of methanolic and aqeous extract of Annona reticulata at doses of 100mg/kg, 200mg/kg and 400mg/kg using the PTZ and MES models were investigated in Swiss Albino Rats. The %protection of the rats was found to increase with an increase in the dose. It was found that at the dose of 400mg/kg, both the extract of the leaves showed very good activity and most animals showed no signs of convulsions. The obtained data from the study suggested the reduction in the duration and delay in the latency of the seizures.Keywords
Annona Reticulata, Antiepileptic Activity, MES, PTZ.References
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- In Vitro Antioxidant Activity of Leaves Extracts of Areca catechu
Abstract Views :293 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutical Chemistry, N.G.S.M. Institute of Pharmaceutical Sciences, Nitte (Deemed to be University) Paneer, Deralakatte, Mangalore-575018, IN
1 Department of Pharmaceutical Chemistry, N.G.S.M. Institute of Pharmaceutical Sciences, Nitte (Deemed to be University) Paneer, Deralakatte, Mangalore-575018, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 4 (2019), Pagination: 1536-1540Abstract
Areca catechu L. (Arecaceae) is a species of palm mainly grown in Asian countries for seed crop. Areca nut leaves are commonly used in traditional systems of medicine against various ailments. There is a need for identifying native natural plant sources to acquire their recognized medicinal properties, which may widen them to use as new therapeutics for various diseases. The present work was aimed to evaluate the in vitro pharmacological screening of the extracts of the leaves of Areca catechu L. by DPPH assay, nitric oxide radical scavenging activity, hydrogen peroxide radical scavenging activity and total antioxidant capacity. The extracts of the leaves of Areca catechu L. showed significant results with the standard ascorbic acid.Keywords
Antioxidant Activity, DPPH, Areca catechu, Nitric Oxide Radical Scavenging Activity, Ascorbic Acid.References
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